Potter star Watson parties with Borrell & other: 2008

Wednesday 3 September 2008

Why Transplanted Insulin Cells Die

�New research can enhance survival of islets transplants and ameliorate treatment of type 1 diabetes.

Transplantation of insulin-producing cell islets, alleged islets of langerhans is an appealing strategy for treatment of type 1 diabetes. But it turns out that these are short-lived, and the procedure needs to be repeated.

Now researchers at Link�ping University and Uppsala University in Sweden hind end show that accumulation of protein aggregatess, amyloid, in the transplanted cells whitethorn be causation their death.

Until now it was not known wherefore this insulin production ceases. The discovery now beingness published in The New England Journal of Medicine may change the course of diabetes research.

Transplant attempts have been carried out for more than 30 years. Hundreds of patients have had healthy insulin-producing islets of Langerhans cured from the pancreas of donors. These transplants, which usually postulate the injection of prison cell islets into the liver, normally go well, and the patients initially don't have to take insulin. But inside a year or deuce years the insulin production will stop from the transplanted cells.

"We have studied this in mice, simply it has naturally been difficult to do so in mankind. Now we have had an chance to examine such transplants in an individual with type 1 diabetes," says Gunilla T. Westermark, helper professor of cell biology at Link�ping University.

In close to half of the cell islets examined, 43 percent, the researchers establish lumps of amyloid.

"We previously know that amyloid production is a symptom of stress that leads to cell death in type 2 diabetes. Perhaps the same thing happens in a transfer, when cells are open to great stress," says Gunilla T. Westermark.

Interestingly, there were quite a few unaffected cubicle islets unexpended in the liver. If we toilet prevent the production of amyloid at an early stage, these cells would be able to stay on to bring about insulin. One possible scheme is to create a drug; another would be to refine the methods used in transplants in order to reduce stress.

Vetenskapsradet (The Swedish Research Council)
http://www.vr.se

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Thursday 14 August 2008

Cusack stalker trial set

Law & disorder

Los Angeles Superior Court Judge Susan Speer ruled Wednesday that Emily Leatherman, 33, wHO is accused of stalk actor John Cusack, is competent to stand trial but cannot represent herself. A court-appointed psychiatrist evaluated Leatherman and said she was "delusional" and "paranoiac." The pass judgment appointed an attorney to represent Leatherman at test, set to begin Sept. 9.

Coke-mobile unmasked

Police in Providence, R.I., said an unmarked car that officers had been drive for several years came with a surprise: a half-pound of cocaine concealed behind the radio. Deputy Police Chief Paul Kennedy said the Ford Taurus was confiscated from a drug dealer in 2000. He added that constabulary search for contraband in confiscated vehicles but sometimes "miss stuff." The cocain was base about trinity weeks agone by a repairman world Health Organization was cannibalizing the motorcar for spare parts.

Worth a try

In coins he trusts

An Ohioan wHO doesn't trust paper money delivered enough coins to cover half the damage of a new pickup truck. Employees at a dealership in the Cincinnati suburb of Springdale aforementioned James Jones, 70, plunked down 16 coffee cans full of coins Tuesday for a Chevrolet Silverado. Salesman David Crisswell aforementioned employees played out 90 proceedings counting coins, which covered half the $16,000 price of the pickup. Jones and his wife, Betty, wrote a chequer for the other half.

Update

Actor pleads non guilty

Actor Shelley Malil, 43, best known for his performance in "The 40-Year-Old Virgin," pleaded not guilty Wednesday to charges of attempted mangle in an attack that left his former lady friend in critical condition with 20 stab wounds, regime said. He faces the possibility of life in prison if convicted, aforementioned San Diego District Attorney spokesman Paul Levikow. The charges against him admit allegations of using a knife, domestic violence and causing grave bodily wound. He is being held in place of $10 million bail. Malil played Haziz, nonpareil of star Steve Carell's co-workers at an electronics store in "The 40-Year-Old Virgin."

Steinbeck revision

A federal appeals court has reversed a ruling that awarded John Steinbeck's son and granddaughter publication rights to 10 of the author's early workings, including "The Grapes of Wrath." The appeals lawcourt said Wednesday that a judge made a misunderstanding when he ruled the works belonged to the son, Thomas Steinbeck, and granddaughter Blake Smyle. The two had won rights previously held by various individuals and organizations, including Penguin Group and the heirs of John Steinbeck's widow, Elaine. The appeals court ordered the lower court judge to rule in favor of Penguin and the heirs of Elaine Steinbeck, who died in April 2003.

People

Fabian to be honored

Fabian Forte, 65, will receive the Harvey Award on Oct. 24 at the James M. Stewart Museum in Stewart's hometown, Indiana, Pa., about 45 miles northeast of Pittsburgh. Fabian appeared in 30 films, including two with Stewart, "Dear Brigitte" and "Mr. Hobbs Takes a Vacation." The awarding, named subsequently Stewart's 1950 film around an invisible rabbit, has previously been given to June Allyson, Janet Leigh, Shirley Jones, Ernest Borgnine and impressionist Rich Little.

Jolie may substitute Cruise

Angelina Jolie is in negotiations to replace Tom Cruise in Philip Noyce's espionage drama with the working title of "Edwin A. Salt" and a by-the-numbers secret plan: Jolie plays a CIA agent wHO has been accused of "being a Russian sleeper spy and must evade capture long enough to establish her innocence," Variety says.

Passages

Darren "Bo" Taylor, 42, a former member of the Crips who brokered a armistice between war-ridden inner-city gangs after the 1992 Los Angeles riots, died Monday of cancer in San Diego.

Don Helms, 81, the steel guitar player whose ache instrumental cry gave musical voice to the anguish and the joy in virtually all the key recordings by country-music titan Hank Williams, died Monday in Nashville, Tenn., of an manifest heart attack.

Today in History

1848: The Oregon Territory was created.

1900: International forces, including U.S. Marines, entered Beijing to put depressed the Boxer Rebellion, which was aimed at purging China of foreign influence.

1908: Rioting erupted in Springfield, Ill., as a white rout, enraged that two black criminal suspects (one later convicted of murder, the other exculpated of rape) had been spirited away from the city clink by authorities, began mount black-owned homes and businesses on fire. At least two blacks and pentad whites were killed in the force. (The sidesplitter helped inspire the universe of the NAACP the following year.)

1945: President Truman announced that Japan had surrendered unconditionally, termination World War II.

1980: Workers went on strike at the Lenin Shipyard in Gdansk, Poland, in a job action that resulted in the creation of the Solidarity labor movement.

2003: A huge blackout hit the northeastern United States and part of Canada; 50 million people lost power.

Today's Birthdays

Author Russell Baker, 83. Rock singer David Crosby, 67. Comedian-actor Steve Martin, 63. Actor Antonio Fargas, 62. Actress Susan Saint James, 62. Author Danielle Steel, 61. Film composer James Horner, 55. Actress Marcia Gay Harden, 49. Former basketball player Earvin "Magic" Johnson, 49. Singer Sarah Brightman, 48. Actress Halle Berry, 42. Actress Catherine Bell, 40.

Seattle Times news services

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Wednesday 6 August 2008

Universal launches Lost Tunes in U.K.

Download depot focused on rare, exclusive tracks

LONDON -- Universal Music Catalog today launches Lost Tunes, an online U.K. download

Friday 27 June 2008

Glastonbury 2008 weather forecast: two days to go

Today's (June 25) weather forecast for this weekend's (June 27-29) Glastonbury festival, according to forecast service Metcheck, predicts hardly any rain during the entire weekend.

According to the service it will be sunny at the festival all day on Friday, with only the tiniest splattering of rain in the afternoon and temperatures hitting 20 degrees celcius.

On Saturday the weather is predicted to be cloudier, although there should only be a tiny amount of rain, with temperatures similar to the previous day.

A similar forecast is given for Sunday, the final day of the festival, which should be less cloudy, slightly colder, but with hardly any chance of rain.

Keep up with all the action from Glastonbury this weekend (June 27-29) as it happens on NME.COM. For news, pictures and blogs keep checking the NME.COM's Glastonbury Festival page. Plus make sure you get next week's issue of NME � on UK newsstands from July 2 � for the ultimate Glastonbury review.

Friday 13 June 2008

Anuvida and Nik Tyndall

Artist: Anuvida and Nik Tyndall

   Genre(s):
Easy Listening

Discography:

Reiki Healing Hands

Year: 1995
Tracks: 5

Friday 6 June 2008

Juno star drops out of Rami horror movie

Actress Ellen Page has pulled out of Sam Raimi's new horror movie 'Drag Me To Hell'.
The 'Juno' star had agreed to play the lead role in the film, however scheduling conflicts have now forced her to withdraw.
Shooting was due to get underway on March 17 in a bid to wrap before the possible Screen Actors Guild strike on June 30, but was then delayed.
However, the new date clashed with Page's forthcoming roles in psychological thriller 'Peacock' and Drew Barrymore's directorial debut 'Whip It!'
A statement from producers Ghost House Pictures and financier Mandate Pictures, read: "We were racing to start production so that we could accommodate Ellen's schedule.
"But like so many other productions trying to start before the potential SAG strike date, this one needed more time and we had to push back the start of production."

Wednesday 21 May 2008

WILLIE NELSON

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Friday 9 May 2008

Spears flees sons' custody hearing

Pop vocalist Britney Spears testament not get her tribulation rights to her sons restored afterward she missed a detention earshot yesterday.
The troubled isaac Merrit Singer arrived at the courthouse yesterday for the good afternoon legal proceeding just got back into her elevator car and left wing a short time afterward without entrance the construction.
According to reports, Spears said: "I'm scared. I want to generate in the car. I'm sledding in the gondola," after she was met by paparazzi when she arrived at the courthouse.
Law reportedly tried to coax the singer to get back come out of her machine later only she shouted "No", in front going the scene.
A court interpreter by and by said that Spears' ex-husband Kevin Federline, world Health Organization testified yesterday, would keep on sole legal and physical custody of the deuce boys "indefinitely".
Federline's lawyer, Fool Vincent Kaplan, said: "The word victory is not something Mr Federline or his advocate would impute to this situation."
He continued: "His hope is that he will be able to parent the children at or so point in the future with participation from the mother."

Artery Eruption & Mangled Atrocity

Scott H. Biram

Artist: Scott H. Biram

   Genre(s):
Other

Discography:

The Dirty Old One Man Band

Year: 2005
Tracks: 14

West Wing star joins Desperate Housewives

Later a lengthy search, the actor world Health Organization volition play Katherine Mayfair's (Dana Delany) ex-husband in 'Desperate Housewives' has been ground.
TV Guide reports that former 'West Wing' star Gary Kale has signed on to flirt the character.
Cole's first episode volition be screened on US TV on 20 April.
The actor's other credits include 'Midnight Caller' and 'Office Space'.
For more on 'Desperate Housewives', read our blog here.

James J.T. Taylor

Madonna's 'Hard Candy' tops Billboard 200

It's a occupy week at the top of the the Billboard 200, with Madonna's "Hard Candy" lead the natural process at No. 1.